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Thermal proteome profiling in bacteria: probing protein state in vivo

Increasing antibiotic resistance urges for new technologies for studying microbes and antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe the thermostability of Escherichia coli proteins in vivo. E. coli had a more thermostable proteome than human cells, with prot...

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Detalles Bibliográficos
Autores principales:	Mateus, André, Bobonis, Jacob, Kurzawa, Nils, Stein, Frank, Helm, Dominic, Hevler, Johannes, Typas, Athanasios, Savitski, Mikhail M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056769/ https://www.ncbi.nlm.nih.gov/pubmed/29980614 http://dx.doi.org/10.15252/msb.20188242

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