Comorbidities increase in-hospital mortality in dengue patients in Brazil

Dengue remains an unmet public health burden. We determined risk factors for dengue in-hospital mortality in Brazil. Of 326,380 hospitalised dengue cases in 9-45-year-old individuals, there were 971 deaths. Risk of dying was 11-times higher in the presence of underlying common comorbidities (renal,...

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Autores principales: Werneck, Guilherme L, Macias, Alejandro E, Mascarenas, Cesar, Coudeville, Laurent, Morley, David, Recamier, Vincent, Guergova-Kuras, Mariana, Puentes-Rosas, Esteban, Baurin, Nicolas, Toh, Myew-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056917/
https://www.ncbi.nlm.nih.gov/pubmed/30043823
http://dx.doi.org/10.1590/0074-02760180082
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author Werneck, Guilherme L
Macias, Alejandro E
Mascarenas, Cesar
Coudeville, Laurent
Morley, David
Recamier, Vincent
Guergova-Kuras, Mariana
Puentes-Rosas, Esteban
Baurin, Nicolas
Toh, Myew-Ling
author_facet Werneck, Guilherme L
Macias, Alejandro E
Mascarenas, Cesar
Coudeville, Laurent
Morley, David
Recamier, Vincent
Guergova-Kuras, Mariana
Puentes-Rosas, Esteban
Baurin, Nicolas
Toh, Myew-Ling
author_sort Werneck, Guilherme L
collection PubMed
description Dengue remains an unmet public health burden. We determined risk factors for dengue in-hospital mortality in Brazil. Of 326,380 hospitalised dengue cases in 9-45-year-old individuals, there were 971 deaths. Risk of dying was 11-times higher in the presence of underlying common comorbidities (renal, infectious, pulmonary disease and diabetes), similar to the risk of dying from severe dengue and much higher with the combination. Ensuring access to integrated dengue preventative measures in individuals aged ≥ 9 years including those with comorbidities may help achieve the WHO objective of 50% reduction in mortality and 25% reduction in morbidity due to dengue by 2020.
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spelling pubmed-60569172018-07-27 Comorbidities increase in-hospital mortality in dengue patients in Brazil Werneck, Guilherme L Macias, Alejandro E Mascarenas, Cesar Coudeville, Laurent Morley, David Recamier, Vincent Guergova-Kuras, Mariana Puentes-Rosas, Esteban Baurin, Nicolas Toh, Myew-Ling Mem Inst Oswaldo Cruz Short Communication Dengue remains an unmet public health burden. We determined risk factors for dengue in-hospital mortality in Brazil. Of 326,380 hospitalised dengue cases in 9-45-year-old individuals, there were 971 deaths. Risk of dying was 11-times higher in the presence of underlying common comorbidities (renal, infectious, pulmonary disease and diabetes), similar to the risk of dying from severe dengue and much higher with the combination. Ensuring access to integrated dengue preventative measures in individuals aged ≥ 9 years including those with comorbidities may help achieve the WHO objective of 50% reduction in mortality and 25% reduction in morbidity due to dengue by 2020. Instituto Oswaldo Cruz, Ministério da Saúde 2018-07-23 /pmc/articles/PMC6056917/ /pubmed/30043823 http://dx.doi.org/10.1590/0074-02760180082 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Werneck, Guilherme L
Macias, Alejandro E
Mascarenas, Cesar
Coudeville, Laurent
Morley, David
Recamier, Vincent
Guergova-Kuras, Mariana
Puentes-Rosas, Esteban
Baurin, Nicolas
Toh, Myew-Ling
Comorbidities increase in-hospital mortality in dengue patients in Brazil
title Comorbidities increase in-hospital mortality in dengue patients in Brazil
title_full Comorbidities increase in-hospital mortality in dengue patients in Brazil
title_fullStr Comorbidities increase in-hospital mortality in dengue patients in Brazil
title_full_unstemmed Comorbidities increase in-hospital mortality in dengue patients in Brazil
title_short Comorbidities increase in-hospital mortality in dengue patients in Brazil
title_sort comorbidities increase in-hospital mortality in dengue patients in brazil
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056917/
https://www.ncbi.nlm.nih.gov/pubmed/30043823
http://dx.doi.org/10.1590/0074-02760180082
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