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APEX1 Polymorphism and Mercaptopurine-Related Early Onset Neutropenia in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Mercaptopurine (MP) is one of the main chemotherapeutics for acute lymphoblastic leukemia (ALL). To improve treatment outcomes, constant MP dose titration is essential to maintain steady drug exposure, while minimizing myelosuppression. We performed two-stage analyses to identify genetic de...

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Detalles Bibliográficos
Autores principales:	Kim, Hyery, Seo, Heewon, Park, Yoomi, Min, Byung-Joo, Seo, Myung-Eui, Park, Kyung Duk, Shin, Hee Young, Kim, Ju Han, Kang, Hyoung Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Cancer Association 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056975/ https://www.ncbi.nlm.nih.gov/pubmed/28882023 http://dx.doi.org/10.4143/crt.2017.351

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