Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia

Recurrent deletions of the CDKN2A/ARF/CDKN2B genes encoded at chromosome 9p21 have been described in both pediatric and adult acute lymphoblastic leukemia (ALL), but their prognostic value remains controversial, with limited data on adult T-ALL. Here, we investigated the presence of homozygous and h...

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Detalles Bibliográficos
Autores principales: Genescà, E., Lazarenkov, A., Morgades, M., Berbis, G., Ruíz-Xivillé, N., Gómez-Marzo, P., Ribera, J., Juncà, J., González-Pérez, A., Mercadal, S., Guardia, R., Artola, M. T., Moreno, M. J., Martínez-López, J., Zamora, L., Barba, P., Gil, C., Tormo, M., Cladera, A., Novo, A., Pratcorona, M., Nomdedeu, J., González-Campos, J., Almeida, M., Cervera, J., Montesinos, P., Batlle, M., Vives, S., Esteve, J., Feliu, E., Solé, F., Orfao, A., Ribera, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057006/
https://www.ncbi.nlm.nih.gov/pubmed/30041662
http://dx.doi.org/10.1186/s13045-018-0639-8

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