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Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain

BACKGROUND: The role of the innate immune system in Alzheimer’s disease (AD) and neurodegenerative disease susceptibility has recently been highlighted in genetic studies. However, we do not know whether risk for inflammatory disease predisposes unaffected individuals to late-life cognitive deficits...

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Detalles Bibliográficos
Autores principales:	Felsky, Daniel, Patrick, Ellis, Schneider, Julie A., Mostafavi, Sara, Gaiteri, Chris, Patsopoulos, Nikolaos, Bennett, David A., De Jager, Philip L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057096/ https://www.ncbi.nlm.nih.gov/pubmed/30041668 http://dx.doi.org/10.1186/s13024-018-0272-6

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