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Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure
BACKGROUND & AIMS: Acute liver failure is a rapidly progressive deterioration of hepatic function resulting in high mortality and morbidity. Metabolic enzymes can translocate to the nucleus to regulate histone acetylation and gene expression. METHODS: Levels and activities of pyruvate dehydrogen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057136/ https://www.ncbi.nlm.nih.gov/pubmed/29580866 http://dx.doi.org/10.1016/j.jhep.2018.03.016 |