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Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057168/ https://www.ncbi.nlm.nih.gov/pubmed/30090753 http://dx.doi.org/10.4103/ajm.AJM_145_17 |
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author | Youssef, Alexey Yaseer, Samar Harfouch, Rim Marouf, Maya Hasan, Foz |
author_facet | Youssef, Alexey Yaseer, Samar Harfouch, Rim Marouf, Maya Hasan, Foz |
author_sort | Youssef, Alexey |
collection | PubMed |
description | Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up. |
format | Online Article Text |
id | pubmed-6057168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-60571682018-08-08 Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria Youssef, Alexey Yaseer, Samar Harfouch, Rim Marouf, Maya Hasan, Foz Avicenna J Med Case Report Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6057168/ /pubmed/30090753 http://dx.doi.org/10.4103/ajm.AJM_145_17 Text en Copyright: © 2018 Avicenna Journal of Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Youssef, Alexey Yaseer, Samar Harfouch, Rim Marouf, Maya Hasan, Foz Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title | Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title_full | Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title_fullStr | Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title_full_unstemmed | Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title_short | Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria |
title_sort | chiclero's ulcer: an unusual presentation of leishmania tropica in syria |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057168/ https://www.ncbi.nlm.nih.gov/pubmed/30090753 http://dx.doi.org/10.4103/ajm.AJM_145_17 |
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