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Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria

Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we...

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Autores principales: Youssef, Alexey, Yaseer, Samar, Harfouch, Rim, Marouf, Maya, Hasan, Foz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057168/
https://www.ncbi.nlm.nih.gov/pubmed/30090753
http://dx.doi.org/10.4103/ajm.AJM_145_17
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author Youssef, Alexey
Yaseer, Samar
Harfouch, Rim
Marouf, Maya
Hasan, Foz
author_facet Youssef, Alexey
Yaseer, Samar
Harfouch, Rim
Marouf, Maya
Hasan, Foz
author_sort Youssef, Alexey
collection PubMed
description Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up.
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spelling pubmed-60571682018-08-08 Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria Youssef, Alexey Yaseer, Samar Harfouch, Rim Marouf, Maya Hasan, Foz Avicenna J Med Case Report Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17(th) century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6057168/ /pubmed/30090753 http://dx.doi.org/10.4103/ajm.AJM_145_17 Text en Copyright: © 2018 Avicenna Journal of Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Youssef, Alexey
Yaseer, Samar
Harfouch, Rim
Marouf, Maya
Hasan, Foz
Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_full Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_fullStr Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_full_unstemmed Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_short Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_sort chiclero's ulcer: an unusual presentation of leishmania tropica in syria
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057168/
https://www.ncbi.nlm.nih.gov/pubmed/30090753
http://dx.doi.org/10.4103/ajm.AJM_145_17
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