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Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey

OBJECTIVES: We aimed to study laryngeal stenosis among hospitalized children in the United States from 2003–2012. We hypothesized that the prevalence of laryngeal stenosis differs by race even when controlling for age, gender, and commonly associated disease conditions. METHODS: We report the result...

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Autores principales: Johnson, Romaine F., Isaiah, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057228/
https://www.ncbi.nlm.nih.gov/pubmed/30062142
http://dx.doi.org/10.1002/lio2.153
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author Johnson, Romaine F.
Isaiah, Amal
author_facet Johnson, Romaine F.
Isaiah, Amal
author_sort Johnson, Romaine F.
collection PubMed
description OBJECTIVES: We aimed to study laryngeal stenosis among hospitalized children in the United States from 2003–2012. We hypothesized that the prevalence of laryngeal stenosis differs by race even when controlling for age, gender, and commonly associated disease conditions. METHODS: We report the results of a cross‐sectional survey of hospitalized patients with laryngeal stenosis. We utilized the Kids Inpatient Database (KID) to estimate the odds of laryngeal stenosis as a function of race using regression analysis. The effects of age, gender, and commonly associated conditions were controlled. RESULTS: There were 13,910 estimated discharges of patients with laryngeal stenosis (95% CI 13,715–14,105) within the study period. This accounts for 55 cases of laryngeal stenosis per 100,000 discharges (overall prevalence = 0.22%). After controlling for age and gender, Black children had the highest likelihood of laryngeal stenosis with OR of 1.9 (95% CI 1.8–2.0, P < .001) along with children classified as Other (OR = 1.2, 95% CI 1.0–1.3, P = .03). White (OR = 0.89, 95% CI 0.83–0.89, P < .001), Hispanic (OR = 0.86, 95% CI 0.80– 0.92, P < .001), and Asian (OR = 0.53, 95% CI 0.43–0.64, P < .001) children were less likely to be diagnosed with laryngeal stenosis while Native Americans (OR = 0.96, 95% CI 0.63–1.45, P = .51) were equally likely. CONCLUSIONS: Laryngeal stenosis is more common among hospitalized Black children, while other racial groups appear to have lower risk. This elevated risk remained when controlling for age, gender, and commonly associated conditions with laryngeal stenosis. LEVEL OF EVIDENCE: 4
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spelling pubmed-60572282018-07-30 Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey Johnson, Romaine F. Isaiah, Amal Laryngoscope Investig Otolaryngol Pediatrics and Development OBJECTIVES: We aimed to study laryngeal stenosis among hospitalized children in the United States from 2003–2012. We hypothesized that the prevalence of laryngeal stenosis differs by race even when controlling for age, gender, and commonly associated disease conditions. METHODS: We report the results of a cross‐sectional survey of hospitalized patients with laryngeal stenosis. We utilized the Kids Inpatient Database (KID) to estimate the odds of laryngeal stenosis as a function of race using regression analysis. The effects of age, gender, and commonly associated conditions were controlled. RESULTS: There were 13,910 estimated discharges of patients with laryngeal stenosis (95% CI 13,715–14,105) within the study period. This accounts for 55 cases of laryngeal stenosis per 100,000 discharges (overall prevalence = 0.22%). After controlling for age and gender, Black children had the highest likelihood of laryngeal stenosis with OR of 1.9 (95% CI 1.8–2.0, P < .001) along with children classified as Other (OR = 1.2, 95% CI 1.0–1.3, P = .03). White (OR = 0.89, 95% CI 0.83–0.89, P < .001), Hispanic (OR = 0.86, 95% CI 0.80– 0.92, P < .001), and Asian (OR = 0.53, 95% CI 0.43–0.64, P < .001) children were less likely to be diagnosed with laryngeal stenosis while Native Americans (OR = 0.96, 95% CI 0.63–1.45, P = .51) were equally likely. CONCLUSIONS: Laryngeal stenosis is more common among hospitalized Black children, while other racial groups appear to have lower risk. This elevated risk remained when controlling for age, gender, and commonly associated conditions with laryngeal stenosis. LEVEL OF EVIDENCE: 4 John Wiley and Sons Inc. 2018-04-16 /pmc/articles/PMC6057228/ /pubmed/30062142 http://dx.doi.org/10.1002/lio2.153 Text en © 2018 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Pediatrics and Development
Johnson, Romaine F.
Isaiah, Amal
Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title_full Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title_fullStr Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title_full_unstemmed Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title_short Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey
title_sort laryngeal stenosis among hospitalized children: results from a nationwide cross‐sectional survey
topic Pediatrics and Development
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057228/
https://www.ncbi.nlm.nih.gov/pubmed/30062142
http://dx.doi.org/10.1002/lio2.153
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