Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity

Twenty-five piperidines were studied as potential radical scavengers and antitumor agents. Quantitative interaction of compounds with ctDNA using spectroscopic techniques was also evaluated. Our results demonstrate that the evaluated piperidines possesses different abilities to scavenge the radical...

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Detalles Bibliográficos
Autores principales: Das, Suvankar, da Silva, Cristiane J., Silva, Marina de M., Dantas, Maria Dayanne de A., de Fátima, Ângelo, Góis Ruiz, Ana Lúcia T., da Silva, Cleiton M., de Carvalho, João Ernesto, Santos, Josué C.C., Figueiredo, Isis M., da Silva-Júnior, Edeildo F., de Aquino, Thiago M., de Araújo-Júnior, João X., Brahmachari, Goutam, Modolo, Luzia Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057241/
https://www.ncbi.nlm.nih.gov/pubmed/30046486
http://dx.doi.org/10.1016/j.jare.2017.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057241/
https://www.ncbi.nlm.nih.gov/pubmed/30046486
http://dx.doi.org/10.1016/j.jare.2017.10.010

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