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Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity
Twenty-five piperidines were studied as potential radical scavengers and antitumor agents. Quantitative interaction of compounds with ctDNA using spectroscopic techniques was also evaluated. Our results demonstrate that the evaluated piperidines possesses different abilities to scavenge the radical...
Autores principales: | Das, Suvankar, da Silva, Cristiane J., Silva, Marina de M., Dantas, Maria Dayanne de A., de Fátima, Ângelo, Góis Ruiz, Ana Lúcia T., da Silva, Cleiton M., de Carvalho, João Ernesto, Santos, Josué C.C., Figueiredo, Isis M., da Silva-Júnior, Edeildo F., de Aquino, Thiago M., de Araújo-Júnior, João X., Brahmachari, Goutam, Modolo, Luzia Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057241/ https://www.ncbi.nlm.nih.gov/pubmed/30046486 http://dx.doi.org/10.1016/j.jare.2017.10.010 |
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