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LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells
B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious, autoimmune, and malignant diseases. Here, we have identified a natural plasma cell subset that distinctively expresses the inhibitory receptor LAG-3 and mediates this function in vivo. These plasma cells also e...
Autores principales: | Lino, Andreia C., Dang, Van Duc, Lampropoulou, Vicky, Welle, Anna, Joedicke, Jara, Pohar, Jelka, Simon, Quentin, Thalmensi, Jessie, Baures, Aurelia, Flühler, Vinciane, Sakwa, Imme, Stervbo, Ulrik, Ries, Stefanie, Jouneau, Luc, Boudinot, Pierre, Tsubata, Takeshi, Adachi, Takahiro, Hutloff, Andreas, Dörner, Thomas, Zimber-Strobl, Ursula, de Vos, Alex F., Dahlke, Katja, Loh, Gunnar, Korniotis, Sarantis, Goosmann, Christian, Weill, Jean-Claude, Reynaud, Claude-Agnès, Kaufmann, Stefan H.E., Walter, Jörn, Fillatreau, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057275/ https://www.ncbi.nlm.nih.gov/pubmed/30005826 http://dx.doi.org/10.1016/j.immuni.2018.06.007 |
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