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Loss of KIBRA function activates EGFR signaling by inducing AREG

The Hippo signaling pathway is a central regulator of organ size, tissue homeostasis, and tumorigenesis. KIBRA is a member of the WW domain-containing protein family and has recently been reported to be an upstream protein in the Hippo signaling pathway. However, the clinical significance of KIBRA d...

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Detalles Bibliográficos
Autores principales: Mussell, Ashley L., Denson, Kayla E., Shen, He, Chen, Yanmin, Yang, Nuo, Frangou, Costa, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057453/
https://www.ncbi.nlm.nih.gov/pubmed/30042827
http://dx.doi.org/10.18632/oncotarget.25724