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Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

Oocytes have a remarkable ability to reactivate silenced genes in somatic cells. However, it is not clear how the chromatin architecture of somatic cells affects this transcriptional reprogramming. Here, we investigated the relationship between the chromatin opening and transcriptional activation. W...

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Detalles Bibliográficos
Autores principales:	Miyamoto, Kei, Nguyen, Khoi T., Allen, George E., Jullien, Jerome, Kumar, Dinesh, Otani, Tomoki, Bradshaw, Charles R., Livesey, Frederick J., Kellis, Manolis, Gurdon, John B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057489/ https://www.ncbi.nlm.nih.gov/pubmed/29996092 http://dx.doi.org/10.1016/j.celrep.2018.06.030

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