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Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care

INTRODUCTION: Increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: A hospital-based retrospective rev...

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Autores principales: Onyango, Oscar, Sitati, Sarah, Amolo, Lucia, Murila, Florence, Wariua, Susan, Nyamu, Gacheri, Lango, Moses, Patel, Atul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057580/
https://www.ncbi.nlm.nih.gov/pubmed/30050616
http://dx.doi.org/10.11604/pamj.2018.29.152.14046
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author Onyango, Oscar
Sitati, Sarah
Amolo, Lucia
Murila, Florence
Wariua, Susan
Nyamu, Gacheri
Lango, Moses
Patel, Atul
author_facet Onyango, Oscar
Sitati, Sarah
Amolo, Lucia
Murila, Florence
Wariua, Susan
Nyamu, Gacheri
Lango, Moses
Patel, Atul
author_sort Onyango, Oscar
collection PubMed
description INTRODUCTION: Increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: A hospital-based retrospective review of the records of premature infants screened for ROP between January 2010 and December 2015. Records of all premature infants screened for ROP in the neonatal unit and outpatient eye clinic were extracted. Information on Birth weights, Gestational age, Maternal risk factors (mode of delivery, pre-eclampsia/eclampsia) and Neonatal risk factors (neonatal sepsis, days on oxygen, blood transfusion) was recorded in a questionnaire then analysed. RESULTS: 103 infants were included in the study. Mean gestational age was 29.9 ± 2.2 weeks and the mean birth weight was 1280.1 ± 333.0 grams. Forty-three infants were diagnosed with ROP, a prevalence of 41.7%. Majority of these had Stage 1 or 2 ROP in Zone II, which spontaneously regressed with follow up. Nine infants were diagnosed with vision-threatening ROP (any Zone I disease or Stage 2/3 disease in Zone II with plus disease), a prevalence of 20.9%. All of these underwent laser treatment in the neonatal unit. The most significant risk factor was low gestational age. Other risk factors identified were: low birth weight and blood transfusions. CONCLUSION: ROP prevalence in sub-saharan Africa will match those in middle-income and high income countries in neonatal units with advanced care and low mortality.
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spelling pubmed-60575802018-07-26 Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care Onyango, Oscar Sitati, Sarah Amolo, Lucia Murila, Florence Wariua, Susan Nyamu, Gacheri Lango, Moses Patel, Atul Pan Afr Med J Research INTRODUCTION: Increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban Kenya. METHODS: A hospital-based retrospective review of the records of premature infants screened for ROP between January 2010 and December 2015. Records of all premature infants screened for ROP in the neonatal unit and outpatient eye clinic were extracted. Information on Birth weights, Gestational age, Maternal risk factors (mode of delivery, pre-eclampsia/eclampsia) and Neonatal risk factors (neonatal sepsis, days on oxygen, blood transfusion) was recorded in a questionnaire then analysed. RESULTS: 103 infants were included in the study. Mean gestational age was 29.9 ± 2.2 weeks and the mean birth weight was 1280.1 ± 333.0 grams. Forty-three infants were diagnosed with ROP, a prevalence of 41.7%. Majority of these had Stage 1 or 2 ROP in Zone II, which spontaneously regressed with follow up. Nine infants were diagnosed with vision-threatening ROP (any Zone I disease or Stage 2/3 disease in Zone II with plus disease), a prevalence of 20.9%. All of these underwent laser treatment in the neonatal unit. The most significant risk factor was low gestational age. Other risk factors identified were: low birth weight and blood transfusions. CONCLUSION: ROP prevalence in sub-saharan Africa will match those in middle-income and high income countries in neonatal units with advanced care and low mortality. The African Field Epidemiology Network 2018-03-15 /pmc/articles/PMC6057580/ /pubmed/30050616 http://dx.doi.org/10.11604/pamj.2018.29.152.14046 Text en © Oscar Onyango et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Onyango, Oscar
Sitati, Sarah
Amolo, Lucia
Murila, Florence
Wariua, Susan
Nyamu, Gacheri
Lango, Moses
Patel, Atul
Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title_full Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title_fullStr Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title_full_unstemmed Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title_short Retinopathy of prematurity in Kenya: prevalence and risk factors in a hospital with advanced neonatal care
title_sort retinopathy of prematurity in kenya: prevalence and risk factors in a hospital with advanced neonatal care
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057580/
https://www.ncbi.nlm.nih.gov/pubmed/30050616
http://dx.doi.org/10.11604/pamj.2018.29.152.14046
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