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Modelling how responsiveness to interferon improves interferon-free treatment of hepatitis C virus infection

Direct-acting antiviral agents (DAAs) for hepatitis C treatment tend to fare better in individuals who are also likely to respond well to interferon-alpha (IFN), a surprising correlation given that DAAs target specific viral proteins whereas IFN triggers a generic antiviral immune response. Here, we...

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Detalles Bibliográficos
Autores principales: Venugopal, Vishnu, Padmanabhan, Pranesh, Raja, Rubesh, Dixit, Narendra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057683/
https://www.ncbi.nlm.nih.gov/pubmed/30001324
http://dx.doi.org/10.1371/journal.pcbi.1006335