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Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats

OBJECTIVE: Mild hypothermia has a protective effect on ischemic stroke, but the mechanisms remain elusive. Here, we investigated microRNA (miRNA) profiles and the specific role of miRNAs in ischemic stroke treated with mild hypothermia. MATERIALS AND METHODS: Male adult Sprague Dawley rats were subj...

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Detalles Bibliográficos
Autores principales: Liu, Xiangrong, Wu, Di, Wen, Shaohong, Zhao, Shunying, Xia, Ao, Li, Fang, Ji, Xunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057705/
https://www.ncbi.nlm.nih.gov/pubmed/30276328
http://dx.doi.org/10.4103/bc.bc_15_17