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Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis

Toxoplasma gondii transmitted from blood donors to receiving patients has become a concern as numerous articles about the epidemiology of T. gondii infection in blood donors from different provinces have been published in China. This study aimed to evaluate the seroprevalence of T. gondii infection...

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Autores principales: Wang, Taiwu, Han, Yifang, Pan, Zuanqin, Wang, Hengzhong, Yuan, Meng, Lin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057739/
https://www.ncbi.nlm.nih.gov/pubmed/30040610
http://dx.doi.org/10.1051/parasite/2018037
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author Wang, Taiwu
Han, Yifang
Pan, Zuanqin
Wang, Hengzhong
Yuan, Meng
Lin, Hong
author_facet Wang, Taiwu
Han, Yifang
Pan, Zuanqin
Wang, Hengzhong
Yuan, Meng
Lin, Hong
author_sort Wang, Taiwu
collection PubMed
description Toxoplasma gondii transmitted from blood donors to receiving patients has become a concern as numerous articles about the epidemiology of T. gondii infection in blood donors from different provinces have been published in China. This study aimed to evaluate the seroprevalence of T. gondii infection in Chinese blood donors using a meta-analysis. A total of 40 eligible studies, published from 1986 to 2017 and covering 18 provinces and municipalities were included. Among a total of 49,784 Chinese blood donors, the overall IgG seroprevalence of T. gondii infection was 6.26% (95% CI: 4.62%–8.13%). The highest prevalence was in the Northeast of China and the lowest in Central China. The infection rate increased slowly over the years, but not significantly. A statistically significant correlation was found between the seroprevalence of T. gondii infection and the detection method and educational level (p < 0.01). There was no relationship between age, gender, occupation and blood type and seroprevalence of T. gondii (p > 0.05). The prevalence of antibodies to T. gondii in Chinese blood donors was lower than in other countries, but the risk of transfusion-transmitted toxoplasmosis still exits. More concise methods are still needed to evaluate the possibility of transfusion-transmitted toxoplasmosis from blood donors.
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spelling pubmed-60577392018-08-03 Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis Wang, Taiwu Han, Yifang Pan, Zuanqin Wang, Hengzhong Yuan, Meng Lin, Hong Parasite Research Article Toxoplasma gondii transmitted from blood donors to receiving patients has become a concern as numerous articles about the epidemiology of T. gondii infection in blood donors from different provinces have been published in China. This study aimed to evaluate the seroprevalence of T. gondii infection in Chinese blood donors using a meta-analysis. A total of 40 eligible studies, published from 1986 to 2017 and covering 18 provinces and municipalities were included. Among a total of 49,784 Chinese blood donors, the overall IgG seroprevalence of T. gondii infection was 6.26% (95% CI: 4.62%–8.13%). The highest prevalence was in the Northeast of China and the lowest in Central China. The infection rate increased slowly over the years, but not significantly. A statistically significant correlation was found between the seroprevalence of T. gondii infection and the detection method and educational level (p < 0.01). There was no relationship between age, gender, occupation and blood type and seroprevalence of T. gondii (p > 0.05). The prevalence of antibodies to T. gondii in Chinese blood donors was lower than in other countries, but the risk of transfusion-transmitted toxoplasmosis still exits. More concise methods are still needed to evaluate the possibility of transfusion-transmitted toxoplasmosis from blood donors. EDP Sciences 2018-07-23 /pmc/articles/PMC6057739/ /pubmed/30040610 http://dx.doi.org/10.1051/parasite/2018037 Text en © T. Wang et al., published by EDP Sciences, 2018 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Taiwu
Han, Yifang
Pan, Zuanqin
Wang, Hengzhong
Yuan, Meng
Lin, Hong
Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title_full Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title_fullStr Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title_full_unstemmed Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title_short Seroprevalence of Toxoplasma gondii infection in blood donors in mainland China: a systematic review and meta-analysis
title_sort seroprevalence of toxoplasma gondii infection in blood donors in mainland china: a systematic review and meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057739/
https://www.ncbi.nlm.nih.gov/pubmed/30040610
http://dx.doi.org/10.1051/parasite/2018037
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