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Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites

Chloroquine (CQ) treatment failure in Plasmodium falciparum parasites has been documented for decades, but the pharmacological explanation of this phenotype is not fully understood. Current concepts attribute CQ resistance to reduced accumulation of the drug at a given external CQ concentration ([CQ...

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Detalles Bibliográficos
Autores principales:	Reiling, Sarah J., Krohne, Georg, Friedrich, Oliver, Geary, Timothy G., Rohrbach, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057915/ https://www.ncbi.nlm.nih.gov/pubmed/30042399 http://dx.doi.org/10.1038/s41598-018-29422-6

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