Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats

Presynaptic active zone proteins play a crucial role in regulating synaptic plasticity. Although the ubiquitin–proteasome system underlying the degradation of the presynaptic active zone protein is well established, the contribution of this machinery to regulating spinal plasticity during neuropathi...

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Detalles Bibliográficos
Autores principales: Hsieh, Ming-Chun, Ho, Yu-Cheng, Lai, Cheng-Yuan, Chou, Dylan, Chen, Gin-Den, Lin, Tzer-Bin, Peng, Hsien-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057957/
https://www.ncbi.nlm.nih.gov/pubmed/30042425
http://dx.doi.org/10.1038/s41419-018-0859-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057957/
https://www.ncbi.nlm.nih.gov/pubmed/30042425
http://dx.doi.org/10.1038/s41419-018-0859-4

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