Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression

Chronic kidney disease (CKD) patients accumulate uremic toxins in the body, potentially require dialysis, and can eventually develop cardiovascular disease. CKD incidence has increased worldwide, and preventing CKD progression is one of the most important goals in clinical treatment. In this study,...

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Detalles Bibliográficos
Autores principales: Takada, T., Yamamoto, T., Matsuo, H., Tan, J. K., Ooyama, K., Sakiyama, M., Miyata, H., Yamanashi, Y., Toyoda, Y., Higashino, T., Nakayama, A., Nakashima, A., Shinomiya, N., Ichida, K., Ooyama, H., Fujimori, S., Suzuki, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057959/
https://www.ncbi.nlm.nih.gov/pubmed/30042379
http://dx.doi.org/10.1038/s41598-018-29208-w

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