Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

Immunotherapy is emerging as a new pillar of cancer treatment with potential to cure. However, many patients still fail to respond to these therapies. Among the underlying factors, an immunosuppressive tumor microenvironment (TME) plays a major role. Here we show that monocyte-mediated gene delivery...

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Detalles Bibliográficos
Autores principales: Escobar, Giulia, Barbarossa, Luigi, Barbiera, Giulia, Norelli, Margherita, Genua, Marco, Ranghetti, Anna, Plati, Tiziana, Camisa, Barbara, Brombin, Chiara, Cittaro, Davide, Annoni, Andrea, Bondanza, Attilio, Ostuni, Renato, Gentner, Bernhard, Naldini, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057972/
https://www.ncbi.nlm.nih.gov/pubmed/30042420
http://dx.doi.org/10.1038/s41467-018-05315-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057972/
https://www.ncbi.nlm.nih.gov/pubmed/30042420
http://dx.doi.org/10.1038/s41467-018-05315-0

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