A Synthetic Disaccharide Derivative of Diphyllin, TAARD, Activates Human Natural Killer Cells to Secrete Interferon-Gamma via Toll-Like Receptor-Mediated NF-κB and STAT3 Signaling Pathways

Natural products and their derivatives have long been used as pharmacological agents in the fight against cancer. Human natural killer (NK) cells are critical in our immune system in that they are capable of destroying tumor cells directly. However, there are few reports that elucidate the role of n...

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Detalles Bibliográficos
Autores principales: Yi, Long, Chen, Luxi, Guo, Xiaofeng, Lu, Ting, Wang, Haixia, Ji, Xiaotian, Zhang, Jianying, Ren, Yulin, Pan, Pan, Kinghorn, A. Douglas, Huang, Xiaohua, Wang, Li-Shu, Fan, Zhijin, Caligiuri, Michael A., Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058043/
https://www.ncbi.nlm.nih.gov/pubmed/30072983
http://dx.doi.org/10.3389/fimmu.2018.01509

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