Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy

Jejunoileal follicular lymphomas (FLs) are rare and have been reported to undergo histological transformation (HT). We report a case of jejunoileal FL transformation into diffuse large B-cell lymphoma (DLBCL). An 82-year-old woman presented with a 5.5 cm ulcerated jejunal mass, identified through do...

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Autores principales: Nishimura, Tomoyuki, Kuwai, Toshio, Imagawa, Hiroki, Kohno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Reminder of Important Clinical Lesson
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058155/
https://www.ncbi.nlm.nih.gov/pubmed/30021733
http://dx.doi.org/10.1136/bcr-2018-224467
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author Nishimura, Tomoyuki
Kuwai, Toshio
Imagawa, Hiroki
Kohno, Hiroshi
author_facet Nishimura, Tomoyuki
Kuwai, Toshio
Imagawa, Hiroki
Kohno, Hiroshi
author_sort Nishimura, Tomoyuki
collection PubMed
description Jejunoileal follicular lymphomas (FLs) are rare and have been reported to undergo histological transformation (HT). We report a case of jejunoileal FL transformation into diffuse large B-cell lymphoma (DLBCL). An 82-year-old woman presented with a 5.5 cm ulcerated jejunal mass, identified through double-balloon enteroscopy. The histopathology report revealed diffuse atypical lymphoid cells, which confirmed the presence of DLBCL. Neoplastic follicles confirmed the presence of FL. Genetic analysis revealed a match between the FL and DLBCL. Following a segmentectomy and chemotherapy, the patient is in remission. Based on this case, we should consider the possibility of jejunoileal FLs transforming into DLBCL.
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spelling pubmed-60581552018-07-26 Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy Nishimura, Tomoyuki Kuwai, Toshio Imagawa, Hiroki Kohno, Hiroshi BMJ Case Rep Reminder of Important Clinical Lesson Jejunoileal follicular lymphomas (FLs) are rare and have been reported to undergo histological transformation (HT). We report a case of jejunoileal FL transformation into diffuse large B-cell lymphoma (DLBCL). An 82-year-old woman presented with a 5.5 cm ulcerated jejunal mass, identified through double-balloon enteroscopy. The histopathology report revealed diffuse atypical lymphoid cells, which confirmed the presence of DLBCL. Neoplastic follicles confirmed the presence of FL. Genetic analysis revealed a match between the FL and DLBCL. Following a segmentectomy and chemotherapy, the patient is in remission. Based on this case, we should consider the possibility of jejunoileal FLs transforming into DLBCL. BMJ Publishing Group 2018-07-18 /pmc/articles/PMC6058155/ /pubmed/30021733 http://dx.doi.org/10.1136/bcr-2018-224467 Text en © BMJ Publishing Group Limited 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Reminder of Important Clinical Lesson
Nishimura, Tomoyuki
Kuwai, Toshio
Imagawa, Hiroki
Kohno, Hiroshi
Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title_full Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title_fullStr Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title_full_unstemmed Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title_short Transformation of jejunoileal follicular lymphoma into diffuse large B-cell lymphoma detected using double-balloon enteroscopy
title_sort transformation of jejunoileal follicular lymphoma into diffuse large b-cell lymphoma detected using double-balloon enteroscopy
topic Reminder of Important Clinical Lesson
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058155/
https://www.ncbi.nlm.nih.gov/pubmed/30021733
http://dx.doi.org/10.1136/bcr-2018-224467
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