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Detection of Somatic Mutation in Exon 12 of DNA Polymerase β in Ovarian Cancer Tissue Samples

BACKGROUND: DNA polymerase β (pol β) is a key enzyme of base excision repair pathway. It is a 1-kb gene consisting of 14 exons. Its catalytic part lies between exon 8 and exon 14. Exon 12 has a role in deoxyribonucleotide triphosphate selection for nucleotide transferase activity. METHODS: Genomic D...

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Detalles Bibliográficos
Autores principales:	Khanra, Kalyani, Choudhuri, Indranil, Bhattacharyya, Nandan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute 2018
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058182/ https://www.ncbi.nlm.nih.gov/pubmed/29524322 http://dx.doi.org/10.29252/ibj.22.5.355

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