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Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus

To transfer the viral genome into the host cell cytoplasm, internalized influenza A virus (IAV) particles depend on the fusion of the IAV envelope with host endosomal membranes. The antiviral host interferon (IFN) response includes the upregulation of interferon-induced transmembrane protein 3 (IFIT...

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Detalles Bibliográficos
Autores principales:	Kühnl, Alexander, Musiol, Agnes, Heitzig, Nicole, Johnson, Danielle E., Ehrhardt, Christina, Grewal, Thomas, Gerke, Volker, Ludwig, Stephan, Rescher, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058292/ https://www.ncbi.nlm.nih.gov/pubmed/30042202 http://dx.doi.org/10.1128/mBio.01345-18

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