Pantoprazole, an Inhibitor of the Organic Cation Transporter 2, Does Not Ameliorate Cisplatin‐Related Ototoxicity or Nephrotoxicity in Children and Adolescents with Newly Diagnosed Osteosarcoma Treated with Methotrexate, Doxorubicin, and Cisplatin

LESSONS LEARNED. Using a randomized crossover design and continuous variables such as change in hearing threshold and biomarkers of acute renal injury as short‐term endpoints, it was determined that pantoprazole, an organic cation transporter 2 inhibitor, did not ameliorate cisplatin‐associated neph...

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Detalles Bibliográficos
Autores principales: Fox, Elizabeth, Levin, Kristin, Zhu, Yan, Segers, Blair, Balamuth, Naomi, Womer, Richard, Bagatell, Rochelle, Balis, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2018
Materias:
Clinical Trial Results
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058325/
https://www.ncbi.nlm.nih.gov/pubmed/29445029
http://dx.doi.org/10.1634/theoncologist.2018-0037

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