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A Randomized Phase II Study of Metformin plus Paclitaxel/Carboplatin/Bevacizumab in Patients with Chemotherapy‐Naïve Advanced or Metastatic Nonsquamous Non‐Small Cell Lung Cancer
BACKGROUND. In the absence of a targeted oncogenic driver mutation or high programmed death‐ligand 1 expression, systemic therapy with platinum‐based doublet chemotherapy with or without bevacizumab has been the standard treatment in advanced or metastatic non‐small cell lung cancer (NSCLC). Metform...
Autores principales: | Marrone, Kristen A., Zhou, Xian, Forde, Patrick M., Purtell, Michael, Brahmer, Julie R., Hann, Christine L., Kelly, Ronan J., Coleman, Barbara, Gabrielson, Edward, Rosner, Gary L., Ettinger, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AlphaMed Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058336/ https://www.ncbi.nlm.nih.gov/pubmed/29487223 http://dx.doi.org/10.1634/theoncologist.2017-0465 |
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