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Dysregulation of PI3K-Akt-mTOR pathway in brain of streptozotocin-induced type 2 diabetes mellitus in Wistar rats

BACKGROUND: Proteins of the insulin signaling pathway are needed for cell proliferation and development and glucose homeostasis. It is not known whether insulin signalling markers (Foxo1, Gsk3β) can be correlated with the expression on PI3K-Akt-mTOR pathway, which are needed for cell survival and ma...

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Detalles Bibliográficos
Autores principales: Bathina, Siresha, Das, Undurti N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058366/
https://www.ncbi.nlm.nih.gov/pubmed/30041644
http://dx.doi.org/10.1186/s12944-018-0809-2