Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells

BACKGROUND: Glioblastoma (GBM) is a primary brain tumor with a 5-year survival rate of ≤5%. We have shown earlier that GBM-antibody-linked curcumin (CC) and also phytosomal curcumin (CCP) rescue 50–60% of GBM-bearing mice while repolarizing the tumor-associated microglia/macrophages (TAM) from the t...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sumit, Fried, Angela, Hussaini, Rahman, White, Richard, Baidoo, Juliet, Yalamanchi, Sri, Banerjee, Probal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058381/
https://www.ncbi.nlm.nih.gov/pubmed/30041669
http://dx.doi.org/10.1186/s13046-018-0792-5

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