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Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol

BACKGROUND: Metformin is one of the most commonly used drugs for type 2 diabetes mellitus (T2DM). Despite its efficacy and safety, metformin is frequently associated with highly variable glycemic responses, which is hypothesized to be the result of genetic variations in its transport by organic cati...

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Detalles Bibliográficos
Autores principales: Mato, Edith Pascale Mofo, Guewo-Fokeng, Magellan, Faadiel Essop, M., Owira, Peter Mark Oroma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058382/
https://www.ncbi.nlm.nih.gov/pubmed/30041690
http://dx.doi.org/10.1186/s13643-018-0773-y