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Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
Despite research efforts full potential of siRNA-based therapeutics has not yet been fully realized due to a need for suitable, effective delivery formulations. Here, we examine a potential of a new class of water-soluble chitosans as siRNA platform for pulmonary delivery. The system is based on pip...
Autores principales: | Capel, Victoria, Vllasaliu, Driton, Watts, Peter, Clarke, Philip A., Luxton, Dominic, Grabowska, Anna M., Mantovani, Giuseppe, Stolnik, Snjezana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058492/ https://www.ncbi.nlm.nih.gov/pubmed/29493294 http://dx.doi.org/10.1080/10717544.2018.1440668 |
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