Improved intestinal absorption of paclitaxel by mixed micelles self-assembled from vitamin E succinate-based amphiphilic polymers and their transcellular transport mechanism and intracellular trafficking routes

To ensure that antitumor drugs can be effectively transported across intestinal barrier and then quickly released in tumor cells, mixed polymeric micelles (Mix-PMs) were designed and fabricated by combining poly(2-ethyl-2-oxazoline)-vitamin E succinate (PEOz-VES) with TPGS1000 for enhancing intestin...

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Detalles Bibliográficos
Autores principales: Qu, Xiaoyou, Zou, Yang, He, Chuyu, Zhou, Yuanhang, Jin, Yao, Deng, Yunqiang, Wang, Ziqi, Li, Xinru, Zhou, Yanxia, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058530/
https://www.ncbi.nlm.nih.gov/pubmed/29313392
http://dx.doi.org/10.1080/10717544.2017.1419513

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