Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate

PURPOSE: To report on the medical management of meningioma with compression of the optic chiasm associated with the use of cyproterone acetate (CA). CASE REPORT: A 65-year-old woman who was being treated with CA presented with a recent decrease in visual function, leading to discovery of a giant olf...

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Autores principales: Bernat, Anne Laure, Bonnin, Sophie, Labidi, Moujahed, Aldahak, Nouman, Bresson, Damien, Bouazza, Schahrazed, Froelich, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058554/
https://www.ncbi.nlm.nih.gov/pubmed/30090195
http://dx.doi.org/10.4103/jovr.jovr_21_17
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author Bernat, Anne Laure
Bonnin, Sophie
Labidi, Moujahed
Aldahak, Nouman
Bresson, Damien
Bouazza, Schahrazed
Froelich, Sebastien
author_facet Bernat, Anne Laure
Bonnin, Sophie
Labidi, Moujahed
Aldahak, Nouman
Bresson, Damien
Bouazza, Schahrazed
Froelich, Sebastien
author_sort Bernat, Anne Laure
collection PubMed
description PURPOSE: To report on the medical management of meningioma with compression of the optic chiasm associated with the use of cyproterone acetate (CA). CASE REPORT: A 65-year-old woman who was being treated with CA presented with a recent decrease in visual function, leading to discovery of a giant olfactory groove meningioma with compression of the optic chiasm. CA was discontinued immediately, and her visual function improved dramatically. At 13 months, in addition to a significant improvement in visual and neurocognitive symptoms, the tumor volume was reduced by 50%. CONCLUSION: In meningiomas associated with CA, treatment cessation may result in prompt improvement in symptoms and a reduction in tumor volume, even if the tumor is large and causing neurologic impairments.
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spelling pubmed-60585542018-08-08 Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate Bernat, Anne Laure Bonnin, Sophie Labidi, Moujahed Aldahak, Nouman Bresson, Damien Bouazza, Schahrazed Froelich, Sebastien J Ophthalmic Vis Res Case Report PURPOSE: To report on the medical management of meningioma with compression of the optic chiasm associated with the use of cyproterone acetate (CA). CASE REPORT: A 65-year-old woman who was being treated with CA presented with a recent decrease in visual function, leading to discovery of a giant olfactory groove meningioma with compression of the optic chiasm. CA was discontinued immediately, and her visual function improved dramatically. At 13 months, in addition to a significant improvement in visual and neurocognitive symptoms, the tumor volume was reduced by 50%. CONCLUSION: In meningiomas associated with CA, treatment cessation may result in prompt improvement in symptoms and a reduction in tumor volume, even if the tumor is large and causing neurologic impairments. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6058554/ /pubmed/30090195 http://dx.doi.org/10.4103/jovr.jovr_21_17 Text en Copyright: © 2018 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Bernat, Anne Laure
Bonnin, Sophie
Labidi, Moujahed
Aldahak, Nouman
Bresson, Damien
Bouazza, Schahrazed
Froelich, Sebastien
Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title_full Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title_fullStr Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title_full_unstemmed Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title_short Regression of Giant Olfactory Groove Meningioma and Complete Visual Acuity Recovery after Discontinuation of Cyproterone Acetate
title_sort regression of giant olfactory groove meningioma and complete visual acuity recovery after discontinuation of cyproterone acetate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058554/
https://www.ncbi.nlm.nih.gov/pubmed/30090195
http://dx.doi.org/10.4103/jovr.jovr_21_17
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