Controlled release of celecoxib inhibits inflammation, bone cysts and osteophyte formation in a preclinical model of osteoarthritis

Major hallmarks of osteoarthritis (OA) are cartilage degeneration, inflammation and osteophyte formation. COX-2 inhibitors counteract inflammation-related pain, but their prolonged oral use entails the risk for side effects. Local and prolonged administration in biocompatible and degradable drug del...

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Detalles Bibliográficos
Autores principales: Tellegen, A. R., Rudnik-Jansen, I., Pouran, B., de Visser, H. M., Weinans, H. H., Thomas, R. E., Kik, M. J. L., Grinwis, G. C. M., Thies, J. C., Woike, N., Mihov, G., Emans, P. J., Meij, B. P., Creemers, L. B., Tryfonidou, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058666/
https://www.ncbi.nlm.nih.gov/pubmed/29890922
http://dx.doi.org/10.1080/10717544.2018.1482971

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