Multiseed liposomal drug delivery system using micelle gradient as driving force to improve amphiphilic drug retention and its anti-tumor efficacy

To improve drug retention in carriers for amphiphilic asulacrine (ASL), a novel active loading method using micelle gradient was developed to fabricate the ASL-loaded multiseed liposomes (ASL-ML). The empty ML were prepared by hydrating a thin film with empty micelles. Then the micelles in liposomal...

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Detalles Bibliográficos
Autores principales: Zhang, Wenli, Li, Caibin, Jin, Ya, Liu, Xinyue, Wang, Zhiyu, Shaw, John P., Baguley, Bruce C., Wu, Zimei, Liu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058678/
https://www.ncbi.nlm.nih.gov/pubmed/29493300
http://dx.doi.org/10.1080/10717544.2018.1440669

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