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Liver-targeted delivery of insulin-loaded nanoparticles via enterohepatic circulation of bile acids
Liver is the primary acting site of insulin. In this study, we developed innovative nanoparticles for oral and liver-targeted delivery of insulin by using enterohepatic circulation of bile acids. The nanoparticles were produced from cholic acid and quaternary ammonium modified chitosan derivative an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058709/ https://www.ncbi.nlm.nih.gov/pubmed/29791242 http://dx.doi.org/10.1080/10717544.2018.1469685 |