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Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies

Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass metabolism. This study aimed at developing Hal-loaded penetration enhancer-containing spanlastics (PECSs) to increase transdermal permeation of Hal...

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Detalles Bibliográficos
Autores principales:	Fahmy, Abdurrahman M., El-Setouhy, Doaa Ahmed, Ibrahim, Ahmed B., Habib, Basant A., Tayel, Saadia A., Bayoumi, Noha A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058714/ https://www.ncbi.nlm.nih.gov/pubmed/29219628 http://dx.doi.org/10.1080/10717544.2017.1410262

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