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Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2

Aminoglycoside-induced hair cell (HC) loss is a major cause of hearing impairment, and the effective prevention of HC loss remains an unmet medical need. Epigenetic mechanisms have been reported to be involved in protecting cochlear cells against ototoxic drug injury, and in this study we developed...

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Detalles Bibliográficos
Autores principales: Li, Ao, You, Dan, Li, Wenyan, Cui, Yingjie, He, Yingzi, Li, Wen, Chen, Yan, Feng, Xiao, Sun, Shan, Chai, Renjie, Li, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058728/
https://www.ncbi.nlm.nih.gov/pubmed/30799660
http://dx.doi.org/10.1080/10717544.2018.1461277