Cargando…
Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2
Aminoglycoside-induced hair cell (HC) loss is a major cause of hearing impairment, and the effective prevention of HC loss remains an unmet medical need. Epigenetic mechanisms have been reported to be involved in protecting cochlear cells against ototoxic drug injury, and in this study we developed...
Autores principales: | Li, Ao, You, Dan, Li, Wenyan, Cui, Yingjie, He, Yingzi, Li, Wen, Chen, Yan, Feng, Xiao, Sun, Shan, Chai, Renjie, Li, Huawei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058728/ https://www.ncbi.nlm.nih.gov/pubmed/30799660 http://dx.doi.org/10.1080/10717544.2018.1461277 |
Ejemplares similares
-
Inhibition of H3K9me2 Reduces Hair Cell Regeneration after Hair Cell Loss in the Zebrafish Lateral Line by Down-Regulating the Wnt and Fgf Signaling Pathways
por: Tang, Dongmei, et al.
Publicado: (2016) -
MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a
por: Li, Yimeng, et al.
Publicado: (2016) -
Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle
por: You, Dan, et al.
Publicado: (2018) -
Histone deacetylase 1 is required for the development of the zebrafish inner ear
por: He, Yingzi, et al.
Publicado: (2016) -
Bmi1 regulates auditory hair cell survival by maintaining redox balance
por: Chen, Y, et al.
Publicado: (2015)