Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine–docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo

Mitochondrial-targeting therapy was considered to be a promising approach for the efficient treatment of cancer while positive charge induced nonspecific cytotoxicity severely limits its application. To overcome this drawback, a novel mitochondria targeted conjugate triphenylphosphine-docetaxel (TD)...

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Detalles Bibliográficos
Autores principales: Zhang, Jiulong, Yang, Chunrong, Pan, Shuang, Shi, Menghao, Li, Jie, Hu, Haiyang, Qiao, Mingxi, Chen, Dawei, Zhao, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058733/
https://www.ncbi.nlm.nih.gov/pubmed/29513049
http://dx.doi.org/10.1080/10717544.2018.1446475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058733/
https://www.ncbi.nlm.nih.gov/pubmed/29513049
http://dx.doi.org/10.1080/10717544.2018.1446475

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