Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms

Regulatory T (Treg) cells can weaken antitumor immune responses, and inhibition of their function appears to be a promising therapeutic approach in cancer patients. Mice with targeted deletion of the gene encoding the Cl(−)/HCO(3)(−) anion exchanger AE2 (also termed SLC4A2), a membrane-bound carrier...

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Detalles Bibliográficos
Autores principales: Celay, Jon, Lozano, Teresa, Concepcion, Axel R., Beltrán, Elena, Rudilla, Francesc, García-Barchino, María José, Robles, Eloy F., Rabal, Obdulia, de Miguel, Irene, Panizo, Carlos, Casares, Noelia, Oyarzabal, Julen, Prieto, Jesús, Medina, Juan F., Lasarte, Juan José, Martínez-Climent, José Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058773/
https://www.ncbi.nlm.nih.gov/pubmed/29191842
http://dx.doi.org/10.3324/haematol.2017.175687

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