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Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ
Formation of microthrombi is a hallmark of acquired thrombotic thrombocytopenic purpura. These microthrombi originate from insufficient processing of ultra large von Willebrand factor multimers by ADAMTS13 due to the development of anti-ADAMTS13 autoantibodies. Several studies have identified the ma...
Autores principales: | Hrdinová, Johana, Verbij, Fabian C., Kaijen, Paul H.P., Hartholt, Robin B., van Alphen, Floris, Lardy, Neubury, ten Brinke, Anja, Vanhoorelbeke, Karen, Hindocha, Pooja J., De Groot, Anne S., Meijer, Alexander B., Voorberg, Jan, Peyron, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058777/ https://www.ncbi.nlm.nih.gov/pubmed/29567779 http://dx.doi.org/10.3324/haematol.2017.179119 |
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