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Catalytic activation of β-arrestin by GPCRs
β-arrestins are critical regulator and transducer proteins for G protein-coupled receptors (GPCRs). Cellular β-arrestin function is presently thought to require stable and stoichiometric GPCR/β-arrestin scaffold complex formation driven by the phosphorylated GPCR tail. We demonstrate a distinct and...
Autores principales: | Eichel, Kelsie, Jullié, Damien, Barsi-Rhyne, Benjamin, Latorraca, Naomi R., Masureel, Matthieu, Sibarita, Jean-Baptiste, Dror, Ron O., von Zastrow, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058965/ https://www.ncbi.nlm.nih.gov/pubmed/29720660 http://dx.doi.org/10.1038/s41586-018-0079-1 |
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