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Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol
INTRODUCTION: Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059343/ https://www.ncbi.nlm.nih.gov/pubmed/30018092 http://dx.doi.org/10.1136/bmjopen-2017-019542 |
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author | Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto |
author_facet | Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto |
author_sort | Simões, Pedro Augusto |
collection | PubMed |
description | INTRODUCTION: Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome. METHODS AND ANALYSIS: This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a non-pharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life. ETHICS AND DISSEMINATION: The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors. TRIAL REGISTRATION NUMBER: NCT03283735. |
format | Online Article Text |
id | pubmed-6059343 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-60593432018-07-27 Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto BMJ Open Patient-Centred Medicine INTRODUCTION: Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome. METHODS AND ANALYSIS: This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a non-pharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life. ETHICS AND DISSEMINATION: The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors. TRIAL REGISTRATION NUMBER: NCT03283735. BMJ Publishing Group 2018-07-17 /pmc/articles/PMC6059343/ /pubmed/30018092 http://dx.doi.org/10.1136/bmjopen-2017-019542 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Patient-Centred Medicine Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title | Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_full | Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_fullStr | Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_full_unstemmed | Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_short | Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_sort | deprescribing in primary care in portugal (depil17-20): a three-phase observational and experimental study protocol |
topic | Patient-Centred Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059343/ https://www.ncbi.nlm.nih.gov/pubmed/30018092 http://dx.doi.org/10.1136/bmjopen-2017-019542 |
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