Effects of Urocortin 2 Versus Urocortin 3 Gene Transfer on Left Ventricular Function and Glucose Disposal

UCn2 and UCn3 peptides have recently been infused to treat patients with heart failure (HF) but are limited by their short half-lives. A 1-time intravenous injection of virus vectors encoding UCn2 or UCn3 provided sustained increases in plasma concentrations of the peptides. This was associated with...

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Detalles Bibliográficos
Autores principales: Giamouridis, Dimosthenis, Gao, Mei Hua, Lai, N. Chin, Tan, Zhen, Kim, Young Chul, Guo, Tracy, Miyanohara, Atsushi, Blankesteijn, W. Matthijs, Biessen, Erik, Hammond, H. Kirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059348/
https://www.ncbi.nlm.nih.gov/pubmed/30062211
http://dx.doi.org/10.1016/j.jacbts.2017.12.004

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