Cargando…

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis, monitoring, and treatment susceptibility testing in human cancers. However, accurate detection of variant alleles, particularly during untargeted searches, remains a principal obstacle to widespread application of cell-f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hellwig, Sabine, Nix, David A., Gligorich, Keith M., O’Shea, John M., Thomas, Alun, Fuertes, Carrie L., Bhetariya, Preetida J., Marth, Gabor T., Bronner, Mary P., Underhill, Hunter R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059400/ https://www.ncbi.nlm.nih.gov/pubmed/30044795 http://dx.doi.org/10.1371/journal.pone.0197333

Ejemplares similares

The stochastic nature of errors in next-generation sequencing of circulating cell-free DNA
por: Nix, David A., et al.
Publicado: (2020)

Fragment Length of Circulating Tumor DNA
por: Underhill, Hunter R., et al.
Publicado: (2016)

Detection of circulating tumor DNA without a tumor-informed search using next-generation sequencing is a prognostic biomarker in pancreatic ductal adenocarcinoma
por: Affolter, Kajsa E., et al.
Publicado: (2021)

Somalier: rapid relatedness estimation for cancer and germline studies using efficient genome sketches
por: Pedersen, Brent S., et al.
Publicado: (2020)

Leveraging the Fragment Length of Circulating Tumour DNA to Improve Molecular Profiling of Solid Tumour Malignancies with Next-Generation Sequencing: A Pathway to Advanced Non-invasive Diagnostics in Precision Oncology?
por: Underhill, Hunter R.
Publicado: (2021)

Enrichment by hybridisation of long DNA fragments for Nanopore sequencing
por: Eckert, Sabine E., et al.
Publicado: (2016)

Small DNA Pieces in C. elegans Are Intermediates of DNA Fragmentation during Apoptosis
por: Aruscavage, P. Joseph, et al.
Publicado: (2010)

Non-random DNA fragmentation in next-generation sequencing
por: Poptsova, Maria S., et al.
Publicado: (2014)

Spectrum of Microbial Sequences and a Bacterial Cell Wall Antigen in Primary Demyelination Brain Specimens Obtained from Living Patients
por: Kriesel, John D., et al.
Publicado: (2019)

Fragment Enrichment of Circulating Tumor DNA With Low-Frequency Mutations
por: Liu, Xiaojun, et al.
Publicado: (2020)

Increased detection of circulating tumor DNA by short fragment enrichment
por: Liu, Yang, et al.
Publicado: (2021)

The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity
por: Dapprich, Johannes, et al.
Publicado: (2016)

Targeted enrichment of genomic DNA regions for next-generation sequencing
por: Mertes, Florian, et al.
Publicado: (2011)

Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing
por: Ignatov, Konstantin B., et al.
Publicado: (2019)

MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing and PCR errors
por: Schwarz, Michael, et al.
Publicado: (2020)

Enrichment of fetal and maternal long cell‐free DNA fragments from maternal plasma following DNA repair
por: Vong, Joaquim S.L., et al.
Publicado: (2019)

Phylogenetic and Structural Analysis of Polyketide Synthases in Aspergilli
por: Bhetariya, Preetida J., et al.
Publicado: (2016)

Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution
por: Müller, Kristian M., et al.
Publicado: (2005)

Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer()
por: Liu, Xiaoyu, et al.
Publicado: (2019)

Enrichment of Retroviral Sequences in Brain Tissue from Patients with Severe Demyelinating Diseases
por: Kriesel, JD, et al.
Publicado: (2017)

Non Invasive Prenatal Diagnosis of Aneuploidy: Next Generation Sequencing or Fetal DNA Enrichment?
por: Webb, A, et al.
Publicado: (2012)

Electroeluting DNA Fragments
por: Zarzosa-Álvarez, Ana L., et al.
Publicado: (2010)

Sperm DNA fragmentation
por: Franco, Jose G.
Publicado: (2017)

Sperm DNA fragmentation
por: Ahuja, Kamal K.
Publicado: (2017)

PCR-Free Enrichment of Mitochondrial DNA from Human Blood and Cell Lines for High Quality Next-Generation DNA Sequencing
por: Gould, Meetha P., et al.
Publicado: (2015)

Sequencing data of cell-free DNA fragments in living-related liver transplantation for inborn errors of metabolism
por: Zhu, Xiaofan, et al.
Publicado: (2020)

Enrichment of megabase-sized DNA molecules for single-molecule optical mapping and next-generation sequencing
por: Łopacińska-Jørgensen, Joanna M., et al.
Publicado: (2017)

A method of large DNA fragment enrichment for nanopore sequencing in region 22q11.2
por: Lei, Yu-Qing, et al.
Publicado: (2022)

Correction: PCR-Free Enrichment of Mitochondrial DNA from Human Blood and Cell Lines for High Quality Next-Generation DNA Sequencing
por: Gould, Meetha P., et al.
Publicado: (2016)

Variant discovery in targeted resequencing using whole genome amplified DNA
por: Indap, Amit R, et al.
Publicado: (2013)

Understanding sperm DNA fragmentation
por: Majzoub, Ahmad, et al.
Publicado: (2017)

Sperm DNA fragmentation testing
por: Schlegel, Peter N.
Publicado: (2017)

Size-selective separation and overall-amplification of cell-free fetal DNA fragments using PCR-based enrichment
por: Yang, Qiwei, et al.
Publicado: (2017)

Shedding light on dark genes: enhanced targeted resequencing by optimizing the combination of enrichment technology and DNA fragment length
por: Iadarola, Barbara, et al.
Publicado: (2020)

Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans
por: Flood, Carrie L., et al.
Publicado: (2015)

Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA
por: Sawyer, Susanna, et al.
Publicado: (2012)

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures
por: Northam, Matthew R., et al.
Publicado: (2014)

Estimating DNA polymorphism from next generation sequencing data with high error rate by dual sequencing applications
por: He, Ziwen, et al.
Publicado: (2013)

Male Infertility and Sperm DNA Fragmentation
por: Zeqiraj, Afrim, et al.
Publicado: (2018)

Sperm DNA fragmentation in clinical practice
por: Majzoub, Ahmad, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r1b73il7j0olni9r2n0r84f058