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Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson’s disease

Caffeine has been considered a neuroprotective agent against Parkinson’s disease (PD). Recent metabolomic analysis showed that levels of caffeine and its metabolites were decreased in sera from patients with PD compared with those from healthy controls. We focused on theophylline, which is one of th...

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Detalles Bibliográficos
Autores principales:	Ohmichi, Takuma, Kasai, Takashi, Kosaka, Tadashi, Shikata, Keisuke, Tatebe, Harutsugu, Ishii, Ryotaro, Shinomoto, Makiko, Mizuno, Toshiki, Tokuda, Takahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059449/ https://www.ncbi.nlm.nih.gov/pubmed/30044870 http://dx.doi.org/10.1371/journal.pone.0201260

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