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Lentiviral delivery of novel fusion protein IL12/FasTI for cancer immune/gene therapy
Many of the cytokine-based cancer immunotherapies are hindered by the devastating side effects of systemic delivery of the cytokines. To address this problem, we previously described a novel approach to locally achieve high doses of interleukin-12 (IL-12) in tumors and demonstrated that bi-functiona...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059467/ https://www.ncbi.nlm.nih.gov/pubmed/30044833 http://dx.doi.org/10.1371/journal.pone.0201100 |