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An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells
INTRODUCTION: Pharmacological defatting of rat hepatocytes and hepatoma cell lines suggests that the same method could be used to ameliorate macrovesicular steatosis in moderate to severely fatty livers. However there is no data assessing the effects of those drugs on primary human liver cells. We a...
Autores principales: | Boteon, Yuri L., Wallace, Lorraine, Boteon, Amanda P. C. S., Mirza, Darius F., Mergental, Hynek, Bhogal, Ricky H., Afford, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059478/ https://www.ncbi.nlm.nih.gov/pubmed/30044872 http://dx.doi.org/10.1371/journal.pone.0201419 |
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