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An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells

INTRODUCTION: Pharmacological defatting of rat hepatocytes and hepatoma cell lines suggests that the same method could be used to ameliorate macrovesicular steatosis in moderate to severely fatty livers. However there is no data assessing the effects of those drugs on primary human liver cells. We a...

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Detalles Bibliográficos
Autores principales: Boteon, Yuri L., Wallace, Lorraine, Boteon, Amanda P. C. S., Mirza, Darius F., Mergental, Hynek, Bhogal, Ricky H., Afford, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059478/
https://www.ncbi.nlm.nih.gov/pubmed/30044872
http://dx.doi.org/10.1371/journal.pone.0201419

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