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Sequence features governing aggregation or degradation of prion-like proteins

Enhanced protein aggregation and/or impaired clearance of aggregates can lead to neurodegenerative disorders such as Alzheimer’s Disease, Huntington’s Disease, and prion diseases. Therefore, many protein quality control factors specialize in recognizing and degrading aggregation-prone proteins. Prio...

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Detalles Bibliográficos
Autores principales:	Cascarina, Sean M., Paul, Kacy R., Machihara, Satoshi, Ross, Eric D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059496/ https://www.ncbi.nlm.nih.gov/pubmed/30005071 http://dx.doi.org/10.1371/journal.pgen.1007517

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